Pyrrolobenzodiazepines and targeted conjugates

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United States of America Patent

PATENT NO 9707301
SERIAL NO

15182649

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Abstract

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This invention relates to pyrrolobenzodiazepines (PBDs), in particular pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position in each monomer unit, and their inclusion in targeted conjugates. The differing substituent groups may offer advantages in the preparation and use of the compounds, particularly in their biological properties and the synthesis of conjugates, and the biological properties of these conjugates.

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Patent Owner(s)

Patent OwnerAddress
SEAGEN INC21823 30TH DR SE BOTHELL WA 98021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burke, Patrick Bothell, US 34 1463
Howard, Philip Wilson London, GB 126 6227
Jeffrey, Scott Bothell, US 63 1527

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