Process for detergent-free production of outer membrane vesicles of a gram-negative bacterium

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United States of America Patent

PATENT NO 9707286
SERIAL NO

15045424

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Abstract

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The present invention relates to the fields of medical microbiology and vaccines. In particular the invention relates to a process for detergent-free preparation of outer membrane vesicles (OMV) of Gram negative bacteria for use in vaccines, to OMV obtainable by said process, and to a pharmaceutical composition comprising such OMV. The present invention further relates to the use of OMV of the present invention as a medicament in particular for use in a method for eliciting an immune response.

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Patent Owner(s)

Patent OwnerAddress
INTRAVACC B VANTONIE V LEEUWENHOEKLAAN 9 BILTHOVEN 3721 MA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Van, De Waterbeemd Bas Utrecht, NL 2 2
Van, Der Pol Leonardus Aldolfus Groningen, NL 3 2

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