Methods of treating muscular dystrophy

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United States of America Patent

PATENT NO 9707210
SERIAL NO

14776898

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Abstract

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Disclosed herein are α7β1 integrin modulatory agents and methods of using such to treat conditions associated with decreased α7β1 integrin expression or activity, including muscular dystrophy. In one example, methods for treating a subject with muscular dystrophy are disclosed. The methods include administering an effective amount of an α7β1 integrin modulatory agent to the subject with muscular dystrophy, wherein the α7β1 integrin modulatory agent increases α7β1 integrin expression or activity as compared to α7β1 integrin expression or activity prior to treatment, thereby treating the subject with muscular dystrophy. Also disclosed are methods of enhancing muscle regeneration, repair, or maintenance in a subject and methods of enhancing α7β1 integrin expression by use of the disclosed α7β1 integrin modulatory agents. Methods of prospectively preventing or reducing muscle injury or damage in a subject are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA RENOUNR/DRI TECHNOLOGY TRANSFER OFFICE 1664 N VIRGINIA STREET MAIL STOP 321 RENO NV 89557

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burkin, Dean Sparks, US 15 120
Wuebbles, Ryan Sparks, US 13 120

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