Glatiramer acetate human monocytic cell line-based potency assay

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United States of America Patent

PATENT NO 9702866
SERIAL NO

14785800

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Abstract

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The present invention relates to a method to determine the potency of a batch of glatiramer acetate comprising stimulating human monocytic cell line cells with an effective amount of interferon (IFNγ), exposing the cells to a batch of glatiramer acetate, and determining the expression of the monocyte anti-inflammatory cytokine sIL-1Ra or the viability of the cells induced by glatiramer acetate.

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Patent Owner(s)

Patent OwnerAddress
SYNTHON B V6545 CM NIJMEGEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kolen, Sebastianus Martinus Henricus Nijmegen, NL 1 0
Weijts, Francisca Antoinette Adriana Nijmegen, NL 1 0

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