Monoclonal antibody having immunosuppressive activity or antigen binding fragment thereof
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United States of America Patent
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Jul 11, 2017
Grant Date -
Jan 9, 2014
app pub date -
Aug 19, 2011
filing date -
Aug 20, 2010
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Abstract
The present invention relates to a monoclonal antibody having excellent immunosuppressive activity or an antigen binding fragment thereof. More specifically, the present invention relates to a monoclonal antibody or an antigen binding fragment thereof, which binds to a peptide consisting an amino acid sequence represented by SSVLYGGPPSAA (SEQ ID NO: 1) or a conjugate of the peptide and a pharmaceutically acceptable carrier, the monoclonal antibody or an antigen binding fragment thereof having a higher binding affinity for core histone than for histone H1.
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