Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals
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United States of America Patent
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Jul 11, 2017
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Dec 2, 2009
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Dec 2, 2008
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Abstract
The present invention relates to compounds that are useful as metal ligands and which either contain a molecular recognition moiety or can be bound to a molecular recognition moiety and methods of making these compounds. Once the compounds that contain a molecular recognition moiety are coordinated with a suitable metallic radionuclide, the coordinated compounds are useful as radiopharmaceuticals in the areas of radiotherapy and diagnostic imaging. The invention therefore also relates to methods of diagnosis and therapy utilising the radiolabelled compounds of the invention.
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