Method for the diagnosis of myeloid neoplasias and solid tumors
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United States of America Patent
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Jul 4, 2017
Grant Date -
Jan 15, 2015
app pub date -
Feb 7, 2013
filing date -
Feb 8, 2012
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Abstract
The present application relates to an ex vivo or in vitro method to determine the presence or absence of a mutation or a variation in the NF-E2 gene in a sample from a patient suffering from a myeloid neoplasm or solid tumor whereby said method comprises:
- a) obtaining a nucleic acid sample from the patient,b) detecting the presence or absence of a mutation in the nucleic acid sample comprising the NF-E2 gene or a fragment thereof, characterized in that the presence of the mutation is an indication of a myeloid neoplasm or solid tumor, whereby the mutation is determined by comparing the nucleic acid sequence obtained from the sample with SEQ ID NO:1 or the complement thereof.
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