Production of fucosylated glycoproteins

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United States of America Patent

PATENT NO 9695454
APP PUB NO 20150176044A1
SERIAL NO

14402837

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Abstract

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Described herein are compositions including filamentous fungal cells, such as Trichoderma fungal cells, having reduced protease activity and expressing fucosylation pathway. Further described herein are methods for producing a glycoprotein having fucosylated N-glycan, using genetically modified filamentous fungal cells, for example, Trichoderma fungal cells, as the expression system.

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GLYKOS FINLAND OYVIIKINKAARI 6 HELSINKI FI-00790

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hanninen, Anna-Liisa Helsinki, FI 3 6
Huuskonen, Anne Helsinki, FI 23 42
Joensuu, Jussi Tervakoski, FI 3 2
Kanerva, Anne Helsinki, FI 31 117
Landowski, Christopher Helsinki, FI 16 30
Natunen, Jari Vantaa, FI 72 438
Penttila, Merja Helsinki, FI 53 494
Saarinen, Juhani Helsinki, FI 42 215
Salo, Hanna Helsinki, FI 5 52
Saloheimo, Markku Helsinki, FI 37 78
Salovuori, Noora Helsinki, FI 10 30
Viskari, Heli Nummela, FI 3 7
Westerholm-Parvinen, Ann Kirkkonummi, FI 18 56

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