Anti-ED-A immunoconjugates for inflammatory bowel disease

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United States of America Patent

PATENT NO 9695232
SERIAL NO

14431745

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Abstract

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Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.

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PHILOGEN S P ALA LIZZA 7 SIENA 53100

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Jianqing Andover, US 21 366
Neri, Giovanni Siena, IT 16 44
O'Hara, Denise M Reading, US 5 39
Ruzek, Melanie C Acton, US 3 8
Schwager, Kathrin Zurich, CH 12 67

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