Oligooxopiperazines for p53 reactivation
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United States of America Patent
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Jul 4, 2017
Issued Date -
N/A
app pub date -
Jan 21, 2014
filing date -
Jan 19, 2013
priority date (Note) -
In Force
status (Latency Note)
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Abstract
The present invention relates to oligooxopiperazines for reactivating p53. The oligooxopiperazines comprise two or three oxopiperazine rings and substantially mimic helix αB of the C-terminal transactivation domain of Hypoxia-Inducible Factor 1α. Methods of using the oligooxopiperazines are also disclosed. Exemplary oligooxopiperazines include those of Formula I below (wherein A, R1, R2, R3, R4, and B are as defined herein).
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International Classification(s)
- 2014 Application Filing Year
- A61K Class
- 14144 Applications Filed
- 11600 Patents Issued To-Date
- 82.02 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 2 Citation Count
- A61K Class
- 45.09 % this patent is cited more than
- 8 Age
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