Alternative process for the purification of an intermediate in the synthesis of non-ionic X-ray contrast agents

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United States of America Patent

PATENT NO 9695113
SERIAL NO

15100818

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Alternative continuous downstream processes for the production of 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide (“Compound A”) are described. Compound A is a key intermediate in the production of iodixanol and iohexol, which are two of the biggest commercially available non-ionic x-ray contrast media agents.

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GE HEALTHCARE ASNYCOVIEN 1 P O BOX 4220 NYDALEN OSLO 0485

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Askildsen, Arne Lindesnes, NO 7 5
Farbrot, Alf Martin Lindesnes, NO 3 2
Haaland, Torfinn Spangereid, NO 7 4
Kalleberg, Rita Heskestad Lindesnes, NO 4 2
Saanum, Inger Dagny Lindesnes, NO 4 2
Silalahi, Sumihar Lindesnes, NO 3 2

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