Functionalized porous silicon nanoparticles and use thereof in photodynamic therapy
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United States of America Patent
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Jul 4, 2017
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Mar 26, 2015
app pub date -
Mar 26, 2013
filing date -
Mar 27, 2012
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Abstract
Disclosed are nanovectors of formula (I) that can be used simultaneously for the targeting, imaging and treatment, by photodynamic therapy, of cancer cells, and to biodegradable silicon nanoparticles containing a variety of photosensitizing molecules, in particular porphyrins, capable of targeting diseased cells and inducing cell death by excitation in the near-infrared region (>600 nm) in monophotonic and biphotonic modes. In formula (I), (AA) is a porous silicon nanoparticle.
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