α-galactosidase A and 1-deoxygalactonojirimycin co-formulation
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United States of America Patent
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Jul 4, 2017
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Jul 16, 2013
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Jul 17, 2012
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Abstract
The present application provides for compositions comprising α-galactosidase A in combination with an active site-specific chaperone for the α-galactosidase A, and methods for treating Fabry disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an α-galactosidase A enzyme formulation.
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