Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids
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United States of America Patent
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Jun 27, 2017
Grant Date -
Sep 8, 2011
app pub date -
Jan 28, 2011
filing date -
Jan 29, 2010
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Abstract
Methods and materials for determining the presence of at least one nucleic acid in a sample are provided, said methods comprising (1) a purification step using sequence specific hybrid capture; (2) an amplification step; and (3) a detection step using two separate sequence-specific polynucleotide probes. Also provided are nucleic acids comprising SEQ ID NO: 1 to SEQ ID NO: 727 and nucleic acid probes and probe sets comprising the same.
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