Method for measuring beta-lactam antibiotics

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United States of America Patent

PATENT NO 9689021
APP PUB NO 20140243241A1
SERIAL NO

14350646

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Abstract

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The present invention relates to methods for determining the concentration of a free beta-lactam antibiotic in a biological sample. In particular, the present invention relates to methods for measuring a free beta-lactam antibiotic in a biological sample, comprising the steps of: (a) providing at least one class C beta-lactamase, a functional fragment or variant thereof; (b) providing at least one biological sample; (c) contacting said at least one class C beta-lactamase with said at least one biological sample; and (d) determining the concentration of said free beta-lactam antibiotic in said at least one biological sample.

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Patent Owner(s)

  • UNIVERSITÉ CATHOLIQUE DE LOUVAIN;UNIVERSITÉ LIBRE DE BRUXELLES;UNIVERSITÉ DE LIÈGE;UNIVERSITÉ DE MONS-HAINAUT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brans, Alain Beaufays, BE 3 22
De, Coninck Joel Mesvin, BE 5 20
Delmarcelle, Michael Walhain, BE 1 2
Goormaghtigh, Erik Enghien, BE 2 2
Hammaecher, Catherine Pinon, FR 1 2
Joris, Bernard Louveigne, BE 9 54
Marchand, Jacqueline Braine l'Alleud, BE 2 10
Tulkens, Paul Nivelles, BE 1 2

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