MicroRNA compounds and methods for modulating miR-21 activity
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United States of America Patent
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Jun 27, 2017
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Jan 14, 2016
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Apr 25, 2012
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Abstract
Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield potent inhibitors of miR-21 activity. The compositions may be used to inhibit miR-21, and also to treat diseases associated with abnormal expression of miR-21, such as fibrosis and cancer.
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