Compositions, uses, and preparation of platelet lysates
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United States of America Patent
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Jun 27, 2017
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app pub date -
Jun 26, 2012
filing date -
Jun 27, 2011
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Abstract
In certain embodiments, this disclosure describes compositions comprising platelet lysates depleted of fibrinogen. In a further embodiment, the composition further comprises a cell culture medium component. This disclosure also provides a method for preparing the composition, comprising the steps of (a) lysing platelets providing a lysate; (b) removing cell debris; and (c) depleting fibrinogen by forming a removable mass by adding a metal salt such as calcium chloride. Furthermore, the disclosure also describes the product produced using said method.
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