Degradable polycations derived from amino acid vinyl esters
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United States of America Patent
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Jun 27, 2017
Grant Date -
Oct 2, 2014
app pub date -
Jun 16, 2014
filing date -
Jan 18, 2012
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Abstract
Described herein are the synthesis and polymerization of a series of N-Boc-protected amino acid vinyl ester (BAAVE) monomers. Homopolymers and heteropolymers containing the monomers are described, particularly heteropolymers with vinyl ester monomers such as vinyl acetate. Deprotection can be used to produce hydrophilic and hydrophobic polymers that are particular useful in biological applications such as cellular delivery of biological materials.
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