Use of NK-1 receptor antagonists for treating hypomagnesemia, neurogenic inflammation, and cardiac dysfunction associated with EGFR-blocking drugs

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United States of America Patent

PATENT NO 9687493
APP PUB NO 20170014420A1
SERIAL NO

15278192

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides methods for alleviating or preventing the negative physiological side effects associated with the administration of EGFR blocking therapeutics. The disclosure provides, inter alia, methods for treating or preventing: hypomagnesemia, cardiac dysfunction, and skin lesions, which are induced by EGFR blocking drugs, by administering an NK-1 receptor antagonist.

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Patent Owner(s)

Patent OwnerAddress
THE GEORGE WASHINGTON UNIVERSITY1922 F STREET NW WASHINGTON DC 20052

International Classification(s)

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  • 2016 Application Filing Year
  • A61K Class
  • 19101 Applications Filed
  • 13019 Patents Issued To-Date
  • 68.16 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mak, Iu Tong Gaithersburg, US 2 4
Weglicki, William B Potomac, US 8 33

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Patent Citation Ranking

  • 3 Citation Count
  • A61K Class
  • 45.09 % this patent is cited more than
  • 8 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges763281956782001332911183139501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000

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