Compositions and methods of targeting mutant K-Ras

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United States of America Patent

PATENT NO 9687491
SERIAL NO

13601227

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The invention relates to a method of modeling K-Ras proteins with one or more mutations that result in constitutive activity, and identifying compounds that inhibit interactions among activated K-Ras proteins and their upstream and downstream effectors.

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Patent Owner(s)

Patent OwnerAddress
NANTBIO INC9920 JEFFERSON BOULEVARD CULVER CITY CA 90232

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Buzko, Oleksandr Los Angeles, US 22 51
Golovato, Justin Los Angeles, US 15 38
Niazi, Kayvan Los Angeles, US 161 169
Rabizadeh, Shahrooz Los Angeles, US 150 185
Soon-Shiong, Patrick Los Angeles, US 637 13443

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