Oral film containing opiate enteric-release beads

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United States of America Patent

PATENT NO 9687445
APP PUB NO 20130273162A1
SERIAL NO

13445716

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A control release and abuse-resistant opiate drug delivery oral wafer or edible oral film dosage to treat pain and substance abuse is provided. The drug delivery oral wafer or edible oral film dosage includes a controlled release layer containing enteric-release beads dispersed in a polymer matrix. The enteric-release beads are formed from a therapeutic amount of an opioid agonist and/or pharmaceutically acceptable salt thereof and a sub-therapeutic amount of opioid antagonist and/or pharmaceutically acceptable salt thereof coated or encapsulated in an enteric-release polymer. The controlled release polymer matrix dissolves or disintegrates following administration or consumption of the oral wafer or edible oral film, releasing the enteric-release beads to be swallowed, with subsequent absorption of the active ingredients within the patient's intestines.

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Patent Owner(s)

  • LTS LOHMANN THERAPIE-SYSTEME AG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Li, Michael Hsin Chwen Warren, US 2 22

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