Mutants of activation-induced cytidine deaminase (AID) and methods of use

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United States of America Patent

PATENT NO 9683226
SERIAL NO

13262187

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Abstract

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The invention provides functional mutants of activation-induced cytidine deaminase (AID) protein that have increased activity as compared to a wild-type AID protein. The invention also provides nucleic acids encoding the functional AID mutants, and vectors and cells comprising the nucleic acids. The invention further provides methods of using the functional mutant AID proteins.

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Patent OwnerAddress
UNITED KINGDOM RESEARCH AND INNOVATIONWILTSHIRE WILTSHIRE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Neuberger, Michael Cambridge, GB 4 28
Rada, Cristina Cambridge, GB 1 15
Wang, Meng Norwich, GB 519 2984
Yang, Zizhen London, GB 1 15

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