Lipid nanoparticles for gene therapy
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United States of America Patent
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Jun 13, 2017
Grant Date -
Jul 19, 2012
app pub date -
Jul 27, 2010
filing date -
Jul 28, 2009
priority date (Note) -
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Abstract
The present invention relates to a lipid nanoparticle system comprising a lipid component, a cationic surfactant, a non-ionic surfactant, a polysaccharide and, optionally, a positively charged peptide, useful for the release of pharmacologically active molecules, and especially for transfecting genetic material into cells and/or tissues. It also relates to methods for obtaining nanoparticles, to pharmaceutical compositions comprising it, as well as to the use thereof in gene therapy.
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