Methods of synthesis and/or purification of diaminophenothiazinium compounds
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
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Jun 13, 2017
Issued Date -
N/A
app pub date -
Jun 17, 2016
filing date -
Jul 11, 2006
priority date (Note) -
In Force
status (Latency Note)
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Abstract
Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds (“diaminophenothiazinium compounds”) including Methylthioninium Chloride (MTC) (Methylene Blue), and the resulting high purity characterized by a purity greater than 98%, and very low levels of heavy metals and organic impurities Azure A, B, C and MVB. Also disclosed are methods of treatment of a tauopathy or methemoglobinemia in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of the high-purity diaminophenothiazinium compound.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
WISTA LABORATORIES LTD | SINGAPORE 658066 |
International Classification(s)

- 2016 Application Filing Year
- A61K Class
- 19101 Applications Filed
- 13019 Patents Issued To-Date
- 68.16 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Baddeley, Thomas Craven | Old Aberdeen, GB | 21 | 107 |
# of filed Patents : 21 Total Citations : 107 | |||
Marshall, Colin | Old Aberdeen, GB | 55 | 309 |
# of filed Patents : 55 Total Citations : 309 | |||
Sinclair, James Peter | Old Aberdeen, GB | 32 | 141 |
# of filed Patents : 32 Total Citations : 141 | |||
Storey, John Mervyn David | Old Aberdeen, GB | 46 | 176 |
# of filed Patents : 46 Total Citations : 176 | |||
Wischik, Claude Michel | Aberdeen, GB | 68 | 401 |
# of filed Patents : 68 Total Citations : 401 |
Cited Art Landscape
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Patent Citation Ranking
- 3 Citation Count
- A61K Class
- 45.09 % this patent is cited more than
- 8 Age
Forward Cite Landscape
- No Forward Cites to Display

Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Dec 13, 2024 |
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Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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Legal Events
Date | Code | Event | Description |
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Jul 05, 2021 | LAPS | LAPSE FOR FAILURE TO PAY MAINTENANCE FEES | free format text: PATENT EXPIRED FOR FAILURE TO PAY MAINTENANCE FEES (ORIGINAL EVENT CODE: EXP.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
Jul 05, 2021 | STCH | INFORMATION ON STATUS: PATENT DISCONTINUATION | free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
May 30, 2021 | FP | LAPSED DUE TO FAILURE TO PAY MAINTENANCE FEE | Effective Date: May 30, 2021 |
Jan 18, 2021 | FEPP | FEE PAYMENT PROCEDURE | free format text: MAINTENANCE FEE REMINDER MAILED (ORIGINAL EVENT CODE: REM.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
May 30, 2017 | I | Issuance | |
May 10, 2017 | STCF | INFORMATION ON STATUS: PATENT GRANT | free format text: PATENTED CASE |
Apr 02, 2013 | AS | ASSIGNMENT | free format text: CONFIRMATORY LICENSE;ASSIGNOR:CERAMATEC, INC.;REEL/FRAME:033348/0403 Owner name: USAF, OHIO Effective Date: Apr 02, 2013 |
Jun 21, 2011 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:ELANGOVAN, S.;HARTVIGSEN, JOSEPH J.;REEL/FRAME:026679/0341 Owner name: CERAMATEC, INC., UTAH Effective Date: Jun 21, 2011 |
Nov 04, 2010 | P | Published | |
Sep 29, 2008 | F | Filing |

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