Methods, systems, and compositions relating to miRNA-146a

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United States of America Patent

PATENT NO 9670490
SERIAL NO

14761442

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Abstract

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Some embodiments comprise methods, systems, and compositions to promote, improve and/or increase neuronal differentiation, oligodendrocyte differentiation, or neurological outcome or function in a patient in need thereof. Some embodiments also comprise the administration a composition comprising a pharmaceutically effective amount of one or more of a group comprising microRNA-146a, a promoter of microRNA-146a expression, a microRNA-146a mimic, thymosin beta 4, and a phosphodiesterase 5 inhibitor to treat neurological conditions, disease, or injury in mammals, including in human beings.

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Patent Owner(s)

Patent OwnerAddress
HENRY FORD HEALTH SYSTEM1 FORD PLACE DETROIT MI 48202

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chopp, Michael Southfield, US 35 413
Liu, Xianshuang Troy, US 2 6
Wang, Lei Troy, US 2386 21419
Zhang, Zhenggang Troy, US 9 14

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