Production of recombinant proteins with simple glycoforms

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United States of America Patent

PATENT NO 9670271
APP PUB NO 20160272696A1
SERIAL NO

15171977

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides cell lines deficient in mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase I (Mgat1). Also provided are methods for producing the Mga1 deficient cell lines and methods for using the Mgat1 deficient cell lines for the production of recombinant proteins having simple glycoforms.

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Patent Owner(s)

Patent OwnerAddress
SIGMA-ALDRICH CO LLCST LOUIS MO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
George, Henry St. Louis, US 8 73
Kayser, Kevin St. Louis, US 8 21
Lin, Nan St. Louis, US 53 183
Sealover, Natalie St. Louis, US 4 3

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