Conjugate of monomethyl auristatin F and trastuzumab and its use for the treatment of cancer

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United States of America Patent

PATENT NO 9669106
APP PUB NO 20170112943A1
SERIAL NO

14923022

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Abstract

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The present invention relates to an antibody-drug-conjugate or pharmaceutical composition comprising the same. From one aspect, the invention relates to an antibody-drug-conjugate (ADC) comprising an antibody consisting of the Trastuzumab or a biosimilar thereof, said antibody being conjugated to at least one drug consisting of a monomethyl auristatin F derivative. The invention also comprises method of treatment of cancer comprising administering to the subject an effective amount of said antibody-drug-conjugate or composition comprising the same.

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Patent Owner(s)

Patent OwnerAddress
PIERRE FABRE MEDICAMENT45 PLACE ABEL GANCE BOULOGNE-BILLANCOURT 92100

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Goetsch, Liliane Ayze, FR 72 725
Jouhanneaud, Alexandra Bonneville, FR 19 57
Perez, Michel Castres, FR 39 272

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