Targeting human thymidylate kinase induces DNA repair toxicity in malignant tumor cells

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9662328
SERIAL NO

15015878

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to novel TMPK inhibitor and their methods of use. In particular, it relates to novel TMPK inhibitor of Formula (I) and therapeutics that decrease the cellular dTTP level to suppress the growth and inhibit DNA repair in tumor cells and acts as a novel chemosensitizer, which are useful in methods for treating or preventing cancers.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
NATIONAL TAIWAN UNIVERSITYNO 1 SEC 4 ROOSEVELT ROAD DA’AN DIST TAIPEI 10617
NATIONAL YANG-MING UNIVERSITYTAIPEI 112

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, Zee-Fen Taipei, TW 4 0
Fang, Jim-Min Taipei, TW 33 267

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Nov 30, 2024
11.5 Year Payment $7400.00 $3700.00 $1850.00 Nov 30, 2028
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00