Expression vector

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United States of America Patent

PATENT NO 9657310
SERIAL NO

14396929

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Abstract

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Disclosed are a novel expression vector for efficient expression of recombinant proteins in mammalian cells, a mammalian cell transformed with the vector, and a method for production of the mammalian cell. The expression vector is an expression vector for expression of a mammalian protein and includes a gene expression regulatory site, and a gene encoding the protein downstream thereof, and an internal ribosome entry site further downstream thereof, and a gene encoding a glutamine synthetase further downstream thereof, and a dihydrofolate reductase gene downstream of either the same gene expression regulatory site or another gene expression regulatory site in addition to the former.

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Patent Owner(s)

Patent OwnerAddress
JCR PHARMACEUTICALS CO LTD3-19 KASUGA-CHO ASHIYA-SHI HYOGO 6590021 ?6590021

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kakimoto, Shinji Hyogo, JP 10 20
Takahashi, Kenichi Hyogo, JP 380 4379

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