Antibodies specific for sclerostin and methods for increasing bone mineralization
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United States of America Patent
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-
May 23, 2017
Issued Date -
N/A
app pub date -
Mar 19, 2015
filing date -
Jun 16, 2003
priority date (Note) -
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status (Latency Note)
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Abstract
Compositions and methods relating to antibodies that specifically bind to TGF-beta binding proteins are provided. These methods and compositions relate to altering bone mineral density by interfering with the interaction between a TGF-beta binding protein sclerostin and a TGF-beta superfamily member, particularly a bone morphogenic protein. Increasing bone mineral density has uses in diseases and conditions in which low bone mineral density typifies the condition, such as osteopenia, osteoporosis, and bone fractures.
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International Classification(s)
- 2015 Application Filing Year
- A61K Class
- 16157 Applications Filed
- 11882 Patents Issued To-Date
- 73.55 % Issued To-Date
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- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 8 Age
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