Compounds for enzyme inhibition

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United States of America Patent

PATENT NO 9657058
APP PUB NO 20150353601A1
SERIAL NO

14591351

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Abstract

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One aspect of the invention relates to inhibitors that preferentially inhibit immunoproteasome activity over constitutive proteasome activity. In certain embodiments, the invention relates to the treatment of immune related diseases, comprising administering a compound of the invention. In certain embodiments, the invention relates to the treatment of cancer, comprising administering a compound of the invention.

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Patent Owner(s)

Patent OwnerAddress
ONYX THERAPEUTICS INCCALIFORNIA USA CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bennett, Mark K Moraga Town, US 53 621
Laidig, Guy J Menlo Park, US 51 1416
Parlati, Francesco San Francisco, US 32 551
Shenk, Kevin D Palo Alto, US 26 700
Smyth, Mark S Foster City, US 75 1296
Sylvain, Catherine San Mateo, US 73 4859
Zhou, Han-jie Foster City, US 62 791

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