Affinity chromatography matrix
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United States of America Patent
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May 23, 2017
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Nov 28, 2012
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Nov 30, 2011
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Abstract
The invention discloses a polypeptide capable of binding immunoglobulins or immunoglobulin-containing proteins, which polypeptide comprises six or more domains of protein Z or the C domain of protein A or a functional variant thereof. It also discloses separation matrices comprising the polypeptide and methods of using the separation matrices for separation of immunoglobulins or immunoglobulin-containing proteins.
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