Crystallization of epirubicin hydrochloride
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United States of America Patent
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May 23, 2017
Grant Date -
Dec 6, 2012
app pub date -
May 15, 2012
filing date -
May 31, 2011
priority date (Note) -
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Abstract
A crystalline epirubicin hydrochloride and a method for its production are provided. The method for producing the crystalline epirubicin hydrochloride includes the steps: (a) providing epirubicin hydrochloride, (b) producing a mixture containing the provided epirubicin hydrochloride and at least one alcohol selected from the group 1-butanol, 2-butanol, and 1-pentanol, and (c) crystallizing epirubicin hydrochloride from this mixture.
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