Sensor for detecting stem cell differentiation based on electrochemical methods
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United States of America Patent
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May 16, 2017
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Jun 12, 2014
app pub date -
Nov 27, 2013
filing date -
Mar 27, 2009
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Abstract
This invention relates to a sensor for detecting a stem cell differentiation, including (a) an electrode; and (b) a substrate of an alkaline phosphatase. The phosphorylation or dephosphorylation of the substrate for an alkaline phosphatase as a stem cell undifferentiation marker which dephosphorylates its substrate may be measured using an electrical signal in the present sensor. Therefore, the sensor of the present invention enables to electrically detect a stem cell status in a high-throughput manner and to determine the stem cell differentiation.
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