Substituted silaxanthenium red to near-infrared fluorochromes for in vitro and in vivo imaging and detection
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United States of America Patent
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May 16, 2017
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Oct 23, 2014
app pub date -
Mar 17, 2014
filing date -
Mar 15, 2013
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Abstract
The invention provides a family of fluorescent compounds. The compounds are substituted silaxanthenium compounds that can be chemically linked to one or more biomolecules, such as a protein, nucleic acid, and therapeutic small molecule. The compounds can be used for imaging in a variety of medical, biological and diagnostic applications. The dyes are particularly useful for in vitro, in vivo and ex vivo imaging applications.
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