Methods and systems for analysis of fibers and branching structures within an image of a sample
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United States of America Patent
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May 9, 2017
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Jul 30, 2015
app pub date -
Aug 28, 2013
filing date -
Aug 28, 2012
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Abstract
A computer-implemented method and system perform efficient and accurate fiber morphology analysis of fiber-containing biological samples. The images of objects comprising fiber and/or branching structure are obtained by camera and/or other imaging devices. Initial tracing seeds are obtained by variable modules. The adaptive threshold method is utilized for identifying tracing seeds candidates by local Principal Component Analysis (PCA) calculation and sorting out the seeds with low and high score. Each single fiber segment of interest is traced repeatedly utilizing PCA fitting calculation, and individual fiber segments are assembled by performing crossover matching calculation.
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