Cancer diagnosis and treatment of cancer using anti-ROBO1 antibody

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United States of America Patent

PATENT NO 9644029
APP PUB NO 20150291694A1
SERIAL NO

14567653

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Abstract

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A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.

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Patent Owner(s)

Patent OwnerAddress
ABURATANI HIROYUKIMUSASHINO-SHI TOKYO 180-0003

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aburatani, Hiroyuki Tokyo, JP 60 599
Arai, Masahiro Tokyo, JP 131 1875
Fukayama, Masashi Tokyo, JP 3 16
Funahashi, Shin-ichi Tokyo, JP 16 83
Hippo, Yoshitaka Huntington, US 8 54
Ito, Hirotaka Tokyo, JP 80 423
Ito, Yukio Tokyo, JP 143 1703
Kinoshita, Yasuko Tokyo, JP 20 234
Ohtomo, Toshihiko Tokyo, JP 40 450
Watanabe, Akira Tokyo, JP 324 4667

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