Capture purification processes for proteins expressed in a non-mammalian system

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United States of America Patent

PATENT NO 9643997
APP PUB NO 20150361130A1
SERIAL NO

14599336

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Abstract

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Methods of purifying proteins expressed in non-mammalian expression systems in a non-native soluble form directly from cell lysate are disclosed. Methods of purifying proteins expressed in non-mammalian expression systems in a non-native limited solubility form directly from a refold solution are also disclosed. Resin regeneration methods are also provided.

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Patent Owner(s)

Patent OwnerAddress
AMGEN INCONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320-1799

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hart, Roger Loveland, US 23 161
Shultz, Joseph Edward Binningen, CH 14 46

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