Human-derived bacteria that induce proliferation or accumulation of regulatory T cells

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United States of America Patent

PATENT NO 9642881
SERIAL NO

15019068

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Abstract

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Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.

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Patent Owner(s)

  • SCHOOL CORPORATION, AZABU VETERINARY MEDICINE EDUCATIONAL INSTITUTION;THE UNIVERSITY OF TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Atarashi, Koji Tokyo, JP 45 1683
Hattori, Masahira Tokyo, JP 35 795
Honda, Kenya Tokyo, JP 57 1897
Morita, Hidetoshi Sagamihara, JP 28 728
Tanoue, Takeshi Tokyo, JP 58 1819

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