Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs
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United States of America Patent
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May 2, 2017
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app pub date -
Jan 15, 2015
filing date -
Jan 17, 2014
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Abstract
The invention relates to prodrugs for use in the inhibition of histone deacetylase. The prodrugs of the present invention have good aqueous solubility and good aqueous stability. The prodrugs of the invention advantageously are metabolized to the active ingredient in plasma or in the blood stream of a warm-blooded animal. The invention also provides compositions and, and methods for making the prodrugs, and methods for using the prodrugs to treat fungal infections.
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