Multitarget FAAH and COX inhibitors and therapeutical uses thereof

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United States of America Patent

PATENT NO 9630914
APP PUB NO 20150203447A1
SERIAL NO

14420237

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Abstract

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Multitarget inhibitors of the enzymes Fatty Acid Amide Hydrolase (FAAH), Cyclooxygenase-1 (COX-1) and/or Cyclooxygenase-2 (COX-2) having a specific carbamate moiety on the meta or ortho position of the A ring of a substituted biphenyl core and having an halogen in the ortho position of the B ring of the biphenyl core. Also concerns the therapeutical application of the multitarget inhibitors, in particular, in the prevention and treatment of cancer.

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Patent Owner(s)

Patent OwnerAddress
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA1111 FRANKLIN STREET FIFTH FLOOR OAKLAND CA 94607-5200
ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNAVIA ZAMBONI 33 BOLOGNA 40126
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIAVIA MOREGO 30 GENOVA 16163

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cavalli, Andrea S. Lazzaro di Savena, IT 13 6
De, Vivo Marco Genoa, IT 9 1
Favia, Angelo Genoa, IT 1 0
Habrant, Damien Norroy le Veneur, FR 1 0
Migliore, Marco Sassari, IT 10 10
Piomelli, Daniele Irvine, US 43 203
Scarpelli, Rita Rome, IT 28 220

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