Stabilized pemetrexed formulation

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United States of America Patent

PATENT NO 9629844
APP PUB NO 20160120867A1
SERIAL NO

14889749

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Abstract

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The present invention relates to a stabilized pemetrexed formulation, and more specifically, to a stabilized pemetrexed formulation comprising acetylcysteine as an antioxidant and sodium citrate as a buffering agent. Additionally, the present invention relates to a pemetrexed formulation filled in a sealed container, comprising pemetrexed or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the oxygen gas content within the headspace of the container is 3 v/v % or less.

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Patent Owner(s)

Patent OwnerAddress
HK INNO N CORPORATION239 OSONGSAENGMYEONG 2-RO OSONG-EUP HEUNGDEOK-GU CHEONGJU-SI CHUNGCHEONGBUK-DO 28158

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Choi, Ha Yong Yongin-si, KR 3 7
Choi, Nak Hyun Yongin-si, KR 10 39
Jin, Hong Chul Seongnam-si, KR 2 7
Park, Young Joon Seoul, KR 23 75
Shin, Myung Jin Seoul, KR 3 7

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