Method for treating tau-associated diseases

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United States of America Patent

PATENT NO 9629835
SERIAL NO

15238025

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Abstract

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A method for treating tau-associated disease by administering a pharmaceutical composition comprising a quinoline derivative to a subject in need is disclosed. Particularly, a method for treating Alzheimer's disease by administering a pharmaceutical composition comprising a quinoline derivative to a subject in need is disclosed. The two disclosed quinoline derivatives have the inhibition effect for GSK-3β kinase activity, so as the two disclosed quinoline derivatives have the ability for inhibiting tau hyperphosphorylation or reducing tau aggregation.

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NATIONAL TAIWAN NORMAL UNIVERSITYTAIPEI

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hsieh, Hsiu-Mei Taipei, TW 15 10
Lee, Guan-Chiun Taipei, TW 11 27
Lee-Chen, Guey-Jen Taipei, TW 14 7
Sun, Ying-Chieh Taipei, TW 2 1

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