High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
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United States of America Patent
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Apr 25, 2017
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app pub date -
Jul 13, 2009
filing date -
Jul 21, 2008
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Abstract
Granules of racemic sodium ibuprofen dihydrate formed from components specified herein have very desirable properties and can be effectively used in conventional rotary press tableting equipment without operational difficulties often encountered in actual practice. Their preparation by a wet granulation process, the wet granule compositions, formulations adapted for preparation of solid dosage forms utilizing a rotary press, solid dosage forms, and methods of preparing solid dosage forms in a rotary press are also described.
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