Method for estimating GFR (glomerular filtration rate) from measured value of megalin in urine
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United States of America Patent
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Apr 18, 2017
Grant Date -
Jan 7, 2016
app pub date -
Feb 19, 2014
filing date -
Feb 19, 2013
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Abstract
The object of the present invention is to provide a method for estimating the glomerular renal function in a convenient and non-invasive manner. As a result of intensive studies to achieve the above object, the present inventors found that there is a high correlation between the urinary megalin excretion rate and the estimated glomerular filtration rate (eGFR) in renal disease patients, and the glomerular filtration rate (GFR) can be estimated with high probability in a non-invasive manner by measuring the megalin level in the urine. This has led to the completion of the present invention.
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