Peptidic chimeric antigen receptor T cell switches and uses thereof
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United States of America Patent
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Apr 18, 2017
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app pub date -
Apr 16, 2015
filing date -
Oct 15, 2013
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Abstract
Disclosed herein are chimeric antigen receptor effector cells (CAR-ECs) and CAR-EC switches. The switchable CAR-ECs are generally T cells. The one or more chimeric antigen receptors may recognize a peptidic antigen on the CAR-EC switch. The CAR-ECs and switches may be used for the treatment of a condition in a subject in need thereof.
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