Engineering the production of a conformational variant of occidiofungin that has enhanced inhibitory activity against fungal species

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United States of America Patent

PATENT NO 9624270
APP PUB NO 20140147416A1
SERIAL NO

14090679

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Abstract

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Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided.

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Patent Owner(s)

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THE TEXAS A&M UNIVERSITY SYSTEM3369 TAMU COLLEGE STATION TX 77843

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  • 2013 Application Filing Year
  • A61K Class
  • 12711 Applications Filed
  • 11051 Patents Issued To-Date
  • 86.95 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2013201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gu, Ganyu Painter, US 6 14
Lu, Shien College Station, US 7 15
Ravichandran, Akshaya College Station, US 5 2
Smith, James Leif College Station, US 7 6

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  • 1 Citation Count
  • A61K Class
  • 45.09 % this patent is cited more than
  • 8 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges763281956782001332911183139501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000

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