β-lactamase inhibitor compounds

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United States of America Patent

PATENT NO 9623014
SERIAL NO

15056090

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Abstract

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The present invention is directed to compounds which are beta-lacatamase inhibitors. The compounds and their pharmaceutically acceptable salts, are useful in combination with beta-lactam antibiotics, or alone, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to formula (Ia):

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Patent Owner(s)

Patent OwnerAddress
ENTASIS THERAPEUTICS LIMITEDLONDON W2 6BD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bifulco, Neil Sudbury, US 9 57
Bist, Shanta Nashua, US 5 51
Chen, Brendan Sudbury, US 2 8
Comita-Prevoir, Janelle Northborough, US 6 18
Durand-Reville, Thomas Francois Belmont, US 5 15
Dussault, Daemian Lowell, US 2 8
Geng, Bolin Andover, US 23 71
Guler, Satenig Waltham, US 4 10
Huynh, Hoan Waltham, US 16 11
Mcguire, Helen Watertown, US 6 41
Wu, Ye Waltham, US 103 294
Xiong, Hui Chesterbrook, US 80 132
Zhao, Liang Lexington, US 669 2735

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