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United States of America Patent

PATENT NO 9617549
SERIAL NO

14857343

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms, such as Bacillus species having enhanced expression of a protein of interest, wherein one or more chromosomal genes have been inactivated, and preferably wherein one or more chromosomal genes have been deleted from the Bacillus chromosome. In some further embodiments, one or more indigenous chromosomal regions have been deleted from a corresponding wild-type Bacillus host chromosome.

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Patent Owner(s)

Patent OwnerAddress
DANISCO US INC925 PAGE MILL ROAD PALO ALTO CA 94304

International Classification(s)

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  • 2015 Application Filing Year
  • C12R Class
  • 164 Applications Filed
  • 100 Patents Issued To-Date
  • 60.98 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20152016201720182019202020210255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ferrari, Eugenio Reggiolo, IT 27 228
Harbison, Carole Ithaca, US 4 19
Rashid, M Harunur Sunnyvale, US 17 33
Weyler, Walter San Francisco, US 37 357

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Patent Citation Ranking

  • 0 Citation Count
  • C12R Class
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  • 8 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges11 - 1000.050.10.150.20.250.30.350.40.450.50.550.60.650.70.750.80.850.90.9511.05

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11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 11, 2028