Use of PEDF-derived polypeptides for promoting stem cells proliferation and wound healing
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United States of America Patent
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Apr 11, 2017
Grant Date -
Jul 2, 2015
app pub date -
Mar 12, 2015
filing date -
Mar 23, 2011
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Abstract
Disclosed herein is a synthetic peptide, which has an amino acid sequence that has 20-39 amino acid residues. The synthetic peptide has at least 80% amino acid sequence identity to SEQ ID NO: 1, and includes at least 20 consecutive residues that has at least 90% amino acid sequence identity to residues 11-30 of SEQ ID NO: 1. Also disclosed herein are compositions containing the synthetic peptide and applications thereof. According to various embodiments of the present disclosure, the synthetic peptide is useful in promoting stem cells proliferation or wound healing.
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